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Brand Viagra

Brand Viagra is the most popular drug used to treat erectile disorders.

Mechanism of action

The active ingredient of the drug – sildenafil – restores reduced erectile function, increasing blood flow to the penis. The mechanism of action is based on the release of nitric oxide in the cavernous bodies at the time of sexual arousal. Free nitric oxide activates the guanylate cyclase enzyme, stimulating an increase in cGMP, which causes relaxation of the smooth muscle fibers of the corpora cavernosa and an increase in blood flow.

Instructions for use

The drug works for 5 hours. To achieve the desired effect, you must follow some rules:

  • take a tablet approximately 20-30 minutes before the intended sexual intercourse with a small amount of water;
  • it is recommended to use the drug on an empty stomach;
  • exclude the use of alcoholic beverages (a little wine does not hurt you);
  • do not take more than 100 mg of sildenafil per day as it can lead to a negative reaction.

The drug begins to act only in the presence of psychological arousal or physical stimulation. The effect allows you to quickly recover an erection after intercourse. Studies have shown that some men achieved an erection after 10 minutes and it lasted up to 6 hours.

Contraindications

Brand Viagra is not used in the presence of any of the following conditions/diseases:

  • allergy to sildenafil;
  • intolerance of auxiliary components;
  • the simultaneous use of donor preparations of nitric oxide (for example, amyl nitrite) or nitrates;
  • conditions where sexual activity is not recommended (severe heart failure, unstable angina);
  • loss of vision in one eye due to non-arterial anterior ischemic neuropathy of the optic nerve;
  • severe liver dysfunction;
  • arterial hypotension (blood pressure below 90/50 mm Hg);
  • a recent stroke, myocardial infarction;
  • hereditary degenerative changes in the retina (for example, retinitis pigmentosa);
  • minor age.

Pregnancy and lactation

The drug is not intended for use in women.

Overdose

Possible symptoms: visual impairment, headache, flushing, dyspepsia, dizziness, nasal congestion.

In case of an overdose, it’s necessary to take standard supportive measures.

Side effects

  • Neurological disorders: headache, flushing, migraine, ataxia, tremor, weakening reflexes, neuralgia, paresthesia, hypesthesia, depression, fainting, insomnia/drowsiness, dizziness;
  • Ophthalmic disorders: visual impairment (hypersensitivity to light, a change in color perception, blurred vision), conjunctivitis, mydriasis, cataracts, hemorrhages in the eyeball, pain in the eyeballs, xerophthalmia;
  • Otolaryngological disorders: deafness, tinnitus;
  • Respiratory disorders: nasal congestion, pharyngitis, bronchitis, sinusitis, laryngitis, dyspnea, increased cough, increased sputum, bronchial asthma;
  • Cardiovascular disorders: arterial hypotension, tachycardia, orthostatic hypotension, palpitations, angina pectoris, myocardial ischemia, cardiomyopathy, ECG changes, heart failure, AV block, cerebral vascular thrombosis, cardiac arrest;
  • Hematologic disorders: anemia, leukopenia;
  • Gastrointestinal disorders: glossitis, stomatitis, gingivitis, dry mouth, nausea, dysphagia, esophagitis, gastritis, colitis, gastroenteritis, rectal bleeding;
    Metabolic disorders: thirst, hyperuricemia, hypernatremia, gout, labile diabetes, hyper- / hypoglycemia;
  • Genitourinary disorders: urinary tract infections, nocturia, cystitis, frequent urination, urinary incontinence, anorgasmia, impaired ejaculation, gynecomastia, genital edema;
  • Musculoskeletal disorders: arthritis, myalgia, arthrosis, tendon rupture, myasthenia gravis, synovitis, tendosynovitis;
  • Dermatological disorders: contact dermatitis, rash, urticaria, pruritus, herpes simplex, skin ulceration, exfoliative dermatitis, photosensitivity;
  • Other: peripheral edema, pain, sweating, chills, shock, allergic reactions.

Interactions

Do not take Brand Viagra with any of the following medications:

  • nitrates;
  • certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide);
  • recreational drugs called “poppers” containing amyl nitrate, amyl nitrite, or butyl nitrite;
  • alpha-blocker medication (doxazosin, tamsulosin);
  • azole antifungals (itraconazole, ketoconazole); macrolide antibiotics (clarithromycin, erythromycin);
  • HIV protease inhibitors (ritonavir, saquinavir);
  • hepatitis C virus protease inhibitors (boceprevir, telaprevir);
  • mifepristone;
  • rifampin;
  • other products that contain sildenafil or other similar medications for erectile dysfunction or pulmonary hypertension (tadalafil, vardenafil).

Overdose

An overdose of sildenafil can cause severe dizziness, fainting, painful/prolonged erection, passing out or trouble breathing. If you have any severe reactions, call 911.

Special instructions

Fatty foods can slow down the effect of the drug, so it is recommended to eat a light meal before taking Brand Viagra. Alcohol enhances the side effects of the drug and causes a decrease in pressure. It is not recommended to take this drug with grapefruit juice, as this interaction enhances the effect of the sildenafil.

Studies of the effect of sildenafil on the ability to drive vehicles and work with mechanisms have not been carried out. Since clinical studies of the use of sildenafil reported cases of dizziness and visual impairment, before driving or working with mechanisms, patients need to find out their individual reaction to sildenafil tablets.